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	Toxin Name δ-hexatoxin-Hv1a Source Species Hadronyche  versuta (Blue Mountains funnel-web spider) Toxin Group Hexatoxin Description Insecticidal and vertebrate-active toxin from the Blue Mountains funnel-web spider Hadronyche versuta. Its close relative Atrax robustus is one of the most dangerous spiders in the world. This toxin is responsible for the symptoms observed in humans following envenomation by Australian funnel-web spiders. δ-HXTX-Hv1a slows the inactivation of both vertebrate tetrodotoxin-sensitive voltage-gated sodium (Nav) channels and insect para-type sodium channels by binding to site 3 of the channel. It is not known whether δ-HXTX-Hv1a is specific for particular vertebrate Nav subtypes. Pan-neuronal expression in Drosophila is lethal but flies engineered to express the toxin only in pacemaker neurons have profound defects in circadian rhythm but a normal lifespan. An antivenom that neutralizes the effect of the δ-hexatoxins was introduced in Australia in 1981 and there have been no recorded deaths due to bites from Atrax robustus or related funnel-web spiders since this time. Discovered 1988 This toxin last updated on Aug 11, 2019 Taxonomy Current Taxonomy Historic Taxonomy Kingdom Animalia Phylum Arthropoda Class Arachnida Order Araneae Infra-order Mygalomorphae Family Hexathelidae Genus Hadronyche Species versuta Hadronyche versuta Pseudatrax moreaui Atrax versuta Atrax bicolor Aname bicolor Biological Activity Neurotoxin Molecular Target ED50 IC50 Kd Pharmacophore Comment Sodium channel, voltage-gated (para-type) (invertebrate) 0.42  nM For cockroach (Periplaneta americana). Significantly lower binding to locust (Locusta migratoria) sodium channels with Kd of 67 nM. Sodium channel, voltage-gated (vertebrate): Vertebrate NaV channel, non-selective Tetrodotoxin-sensitive voltage-gated sodium channels. Taxon ED50 LD50 PD50 Qualitative Information Mus musculus 45.0  pmol/g In suckling mice (converted from 0.22 mg/kg using a molecular mass of 4847.6 Da) Lucilia cuprina 54.0  pmol/g PD50 at 30 min tested in blowfly larvae Acheta domesticus 770.0  pmol/g 200.0  pmol/g LD50 at 72h; PD50 at 30 min Accessions Source Accession ArachnoServer AS000307 InterPro IPR008017 NCBI_Taxon 6904 PDB 1VTX Pfam PF05353 PIR S00343 ProDom PD026455 PROSITE PS60018 UniProt P13494 Literature References Original Deposition References Brown M.R., Sheumack D.D., Tyler M.I., Howden M.E.H. Biochem. J. 250:401-405(1988). Amino acid sequence of versutoxin, a lethal neurotoxin from the venom of the funnel-web spider Atrax versutus. Other References Chieng B., Howden M.E., Christie M.J. Brain Res. 626:136-42(1993). Australian funnel-web spider toxin, versutoxin, enhances spontaneous synaptic activity in single brain neurons in vitro. Nicholson G.M., Willow M., Howden M.E., Narahashi T. Pflugers Arch. 428:400-9(1994). Modification of sodium channel gating and kinetics by versutoxin from the Australian funnel-web spider Hadronyche versuta. Nicholson G.M., Little M.J., Tyler M., Narahashi T. Toxicon 34:1443-53(1996). Selective alteration of sodium channel gating by Australian funnel-web spider toxins. Fletcher J.I., Chapman B.E., Mackay J.P., Howden M.E.H., King G.F. Structure 5:1525-1535(1997). The structure of versutoxin (delta-atracotoxin-Hv1) provides insights into the binding of site 3 neurotoxins to the voltage-gated sodium channel. Little M.J., Wilson H., Zappia C., Cestele S., Tyler M.I., Martin-Eauclaire M.-F., Gordon D., Nicholson G.M. FEBS Lett. 439:246-252(1998). Delta-atracotoxins from Australian funnel-web spiders compete with scorpion alpha-toxin binding on both rat brain and insect sodium channels. Nicholson G.M., Walsh R., Little M.J., Tyler M.I. Pflugers Arch. 436:117-26(1998). Characterisation of the effects of robustoxin, the lethal neurotoxin from the Sydney funnel-web spider Atrax robustus, on sodium channel activation and inactivation. Grolleau F., Stankiewicz M., Birinyi-Strachan L., Wang X.H., Nicholson G.M., Pelhate M., Lapied B. J. Exp. Biol. 204:711-721(2001). Electrophysiological analysis of the neurotoxic action of a funnel- web spider toxin, delta-atracotoxin-HV1a, on insect voltage-gated Na+ channels. Gilles N., Harrison G., Karbat I., Gurevitz M., Nicholson G.M., Gordon D. Eur. J. Biochem. 269:1500-1510 (2002) Variations in receptor site-3 on rat brain and insect sodium channelshighlighted by binding of a funnel-web spider delta-atracotoxin. Wu Y., Cao G., Pavlicek B., Luo X., Nitabach M.N. PLoS Biol. 6:e273(2008) Phase coupling of a circadian neuropeptide with rest/activity rhythms detected using a membrane-tethered spider toxin Protein Information Disulfide Bonds Left Residue Right Residue Evidence 1 15 Experimentally determined 8 20 Experimentally determined 14 31 Experimentally determined 16 42 Experimentally determined Sequences Peptide Sequences >as:δ-hexatoxin-Hv1a|sp:P13494 Vertebrate and insect toxin from Blue Mountains funnel-web spider Hadronyche versuta. CAKKRNWCGKTEDCCCPMKCVYAWYNEQGSCQSTISALWKKC Full BLAST BLAST mature toxin only >as:δ-hexatoxin-Hv1a_2 Translation of δ-hexatoxin-Hv1a_2 (XenFW299) from the Blue Mountains funnel-web spider Hadronyche versuta. MKITAALYVLFFLTIALGDFTEGNENDLVENLRAELSEADIPLLKKLEAAEDALLEKDFL SHAEEDRSARPKRCAKKRNWCGKTEDCCCPMKCVYAWYNEQGSCQSTISALWKKC Full BLAST BLAST mature toxin only >as:δ-hexatoxin-Hv1a_3 Translation of δ-hexatoxin-Hv1a_3 (XenFW300) from the Blue Mountains funnel-web spider Hadronyche versuta. MKITAALYVLFFLTIALGDFTEGNENDLVENLRAELSEADIPLLKKLEAAEDALLEKDFL SHAEEDRSARPKRCAKKRNWCGKTEDCCCPMKCVYAWYNEQGSCQSTISALWKKC Full BLAST BLAST mature toxin only >as:δ-hexatoxin-Hv1a_4 Translation of δ-hexatoxin-Hv1a_4 (XenFW301) from the Blue Mountains funnel-web spider Hadronyche versuta. MKITAALYVLFFLTIALGDFTEGNENDLVENLRAELSEADIPLLKKLEAAEDALLEKDFL SHAEEDRSARPKRCAKKRNWCGKTEDCCCPMKCVYAWYNEQGSCQSTISALWKKC Full BLAST BLAST mature toxin only >as:δ-hexatoxin-Hv1a_5 Translation of δ-hexatoxin-Hv1a_5 (XenFW304) from the Blue Mountains funnel-web spider Hadronyche versuta. MKITAALYVLFFLTIALGDFTEGNENDLVENLRAELSEADIPLLKKLEAAEDALLEKDFL SHAEEDRSARPKRCAKKRNWCGKTEDCCCPMKCVYAWYNEQGSCQSTISALWKKC Full BLAST BLAST mature toxin only >as:δ-hexatoxin-Hv1a_6 Translation of δ-hexatoxin-Hv1a_6 (XenFW305) from the Blue Mountains funnel-web spider Hadronyche versuta. MKITAALYVLFFLTIALGDFTEGNENDLVENLRAELSEADIPLLKKLEAAEDVLLEKDFL SHAEEDRSARPKRCAKKRNWCGKTEDCCCPMKCVYAWYNEQGSCQSTISALWKKC Full BLAST BLAST mature toxin only >as:δ-hexatoxin-Hv1a_7 Translation of δ-hexatoxin-Hv1a_7 (XenFW306) from the Blue Mountains funnel-web spider Hadronyche versuta. MKIPAALYVLFFLTIALGDFTEGNENDLVENLRAELSEADIPLLKKLEAAEDALLEKDFL SHAEEDRSARPKRCAKKRNWCGKTEDCCCPMKCVYAWYNEQGSCQSTISALWKKC Full BLAST BLAST mature toxin only >as:δ-hexatoxin-Hv1a_8 Translation of δ-hexatoxin-Hv1a_8 (XenFW308) from the Blue Mountains funnel-web spider Hadronyche versuta. MKITAALYVLFFLTIALGDFTEGNENDLVENLRAELSEADIPLLKKLEAAEDALLEKDFL SHAEEDRSARPKRCAKKRNWCGKTEDCCCPMKCVYAWYNEQGSCQSTISALWKKC Full BLAST BLAST mature toxin only >as:δ-hexatoxin-Hv1a_9 Translation of δ-hexatoxin-Hv1a_9 (XenFW309) from the Blue Mountains funnel-web spider Hadronyche versuta. MKITAALYVLFFLTIALGDFTEGNENDLVENLRAELSEADIPLLKKLEAAEDALLEKDFL SHAEEDRSARPKRCAKKRNWCGKTEDCCCPMKCVYAWYNEQGSCQSTISALWKKC Full BLAST BLAST mature toxin only >as:δ-hexatoxin-Hv1a_10 Translation of δ-hexatoxin-Hv1a_10 (XenFW?) from the Blue Mountains funnel-web spider Hadronyche versuta. MKITAALYVLFFLTIALGDFTEGNENDLVENLRAELSEADIPLLKKLEAAEDALLEKDFL SHAEEDRSARPKRCAKKRNWCGKTEDCCCPMKCVYAWYNEQGSCQSTISALWKKC Full BLAST BLAST mature toxin only >as:δ-hexatoxin-Hv1a_11 Translation of δ-hexatoxin-Hv1a_11 (XenFW311) from the Blue Mountains funnel-web spider Hadronyche versuta. MKIPAALYVLFFLTIALGDFTEGNENDLVENLRAELSEADIPLLKKLEAAEDALLEKDFL SHAEEDRSARPKRCAKKRNWCGKTEDCCCPMKCVYAWYNEQGSCQSTISALWKKC Full BLAST BLAST mature toxin only >as:δ-hexatoxin-Hv1a_12 Translation of δ-hexatoxin-Hv1a_12 (XenFW312) from the Blue Mountains funnel-web spider Hadronyche versuta. MKIPAALYVLFFLTIALGDFTEGNENDLVENLRAELSEADIPLLKKLEAAEDALLEKDFL SHAEEDRSARPKRCAKKRNWCGKTEDCCCPMKCVYAWYNEQGSCQSTISALWKKC Full BLAST BLAST mature toxin only >as:δ-hexatoxin-Hv1a_13 Translation of δ-hexatoxin-Hv1a_13 (XenFW313) from the Blue Mountains funnel-web spider Hadronyche versuta. MKITAALYVLFFLTIALGDFTEGNENDLVENLRAELSEADIPLLKKLEAAEDALLEKDFL SHAEEDRSARPKRCAKKRNWCGKTEDCCCPMKCVYAWYNEQGSCQSTISALWKKC Full BLAST BLAST mature toxin only >as:δ-hexatoxin-Hv1a_14 Translation of δ-hexatoxin-Hv1a_14 (XenFW303) from the Blue Mountains funnel-web spider Hadronyche versuta. MKIPAALYVLFFLTIALGDFTEGNENDLVENLRAELSEADIPLLKKLEAAEDALLENDFL PHAEEDRSARPKRCAKKRNWCGKTEDCCCPMKCVYAXYNEQGSCQSTISALWKKC Full BLAST BLAST mature toxin only mRNA Sequences >as:δ-hexatoxin-Hv1a_2 cDNA sequence (XenFW299) for δ-hexatoxin-Hv1a_2 from the Blue Mountains funnel-web spider Hadronyche versuta. GTCTACCTAATGAAAATAACAGCAGCTTTGTACGTGCTCTTCTTTCTGACAATTGCTCTG GGCGACTTTACTGAAGGAAATGAAAATGACCTGGTGGAGAACCTACGTGCGGAACTTTCT GAGGCAGATATTCCACTATTGAAGAAACTGGAAGCAGCTGAAGATGCACTTTTGGAGAAA GATTTCTTGTCACATGCAGAGGAGGACAGAAGTGCACGTCCCAAGAGATGCGCTAAAAAA AGAAATTGGTGTGGTAAGACTGAAGACTGCTGCTGCCCGATGAAATGTGTATATGCCTGG TATAATGAGCAAGGTAGTTGCCAAAGTACTATTAGTGCGCTGTGGAAAAAGTGTTGATTC GCGCAAGCGAGAATTCAACGACCAAATCTCTTGCTCCCACGAGAACAAAAGATAAATCCG TATTAATTTTGAAATTCATGTTTAATTACTCAAATGCAACTGAAGTGAGAAATGTTATTT TAGTTGCTTGTGAACTCCTTCTTCGCCAATAAAATTGCCGTAATGTAATATCATTGAAGA CTAATGAATAAACAAAAACTTGCAATAACTAAAAAAAAAAAAAAAA Full BLAST >as:δ-hexatoxin-Hv1a_3 cDNA sequence (XenFW300) for δ-hexatoxin-Hv1a_3 from the Blue Mountains funnel-web spider Hadronyche versuta. TCTACCATAATGAAAATAACAGCAGCTTTGTACGTGCTCTTCTTTCTGACAATTGCTCTG GGCGACTTTACTGAAGGAAATGAAAATGACCTGGTGGAGAACCTACGTGCGGAACTTTCT GAGGCAGATATTCCACTATTGAAGAAACTGGAAGCAGCTGAAGATGCACTTTTGGAGAAA GATTTCTTGTCACATGCAGAGGAGGACAGAAGTGCACGTCCCAAGAGATGCGCTAAAAAA AGAAATTGGTGTGGTAAGACTGAAGACTGCTGCTGCCCGATGAAATGTGTATATGCCTGG TATAATGAGCAAGGTAGTTGCCAAAGTACTATTAGTGCGCTGTGGAAAAAGTGTTGATTC GCGAAAGCGAGAATTCAACGGCCAAATCTCTTGCTCCCTCGAGAACAAAAGATAAATCCG TATTAATTTTGAAATTCATGTTTAATCACTCAAATGCAACTGAAGTGAGAAATGTTATTT TAGTTGCTTGTGAACTCCTTCTTCGCCAATAAAATTGCCGTAATGTAATATCATTGAAGA CTAATGAATAAACAAAAACTTGCAATAACTAAAAAAAAAAAAAAAAAA Full BLAST >as:δ-hexatoxin-Hv1a_4 cDNA sequence (XenFW301) for δ-hexatoxin-Hv1a_4 from the Blue Mountains funnel-web spider Hadronyche versuta. TCTACCATAATGAAAATAACAGCAGCTTTGTACGTGCTCTTCTTTCTGACAATCGCTCTG GGCGACTTTACTGAAGGAAATGAAAATGACCTGGTGGAGAACCTACGTGCGGAACTTTCT GAGGCAGATATTCCACTATTGAAGAAACTGGAAGCAGCTGAAGATGCACTTTTGGAGAAA GATTTCTTGTCACATGCAGAGGAGGACAGAAGTGCACGTCCCAAGAGATGCGCTAAAAAA AGAAATTGGTGTGGTAAGACTGAAGACTGCTGCTGTCCGATGAAATGTGTATATGCCTGG TATAATGAGCAAGGTAGTTGCCAAAGTACTATTAGTGCGCTGTGGAAAAAGTGTTGATTC GCGAAAGCGAGAATTCAACGGCCAAATCTCTTGCTCCCTCGAGAACAAAAGATAAATCCG TATTAATTTTGAAATTCATGTTTAATCACTCAAATGCAACTGAAGTGAGAAATGTTATTT TAGTTGCTTGTGAACTCCTTCTTCGCCAATAAAATTGCCGTAATGTAATATCATTGAAGA CTAATGAATAAACAAAAACTTGCAATAACTAAAAAAAAAAAAAAAAAAAA Full BLAST >as:δ-hexatoxin-Hv1a_5 cDNA sequence (XenFW304) for δ-hexatoxin-Hv1a_5 from the Blue Mountains funnel-web spider Hadronyche versuta. TCTACCATAATGAAAATAACAGCAGCTTTGTACGTGCTCTTCTTTCTGACAATCGCTCTG GGCGACTTTACTGAAGGAAATGAAAATGACCTGGTGGAGAACCTACGTGCGGAACTTTCT GAGGCAGATATTCCACTATTGAAGAAACTGGAAGCAGCTGAAGATGCACTTTTGGAGAAA GATTTCTTGTCACATGCAGAGGAGGACAGAAGTGCACGTCCCAAGAGATGCGCTAAAAAA AGAAATTGGTGTGGTAAGACTGAAGACTGCTGCTGCCCGATGAAATGTGTATATGCCTGG TATAATGAGCAAGGTAGTTGCCAAAGTACTATTAGTGCGCTGTGGAAAAAGTGTTGATTC GCGAAAGCGAGAATTCAACGGCCAAATCTCTTGCTCCCTCGAGAACAAAAGATAAATCCG TATTAATTTTGAAATTCATGTTTAATCACTCAAATGCAACTGAAGTGAGAAATGTTATTT TAGTTGCTTGTGAACTCCTTCTTCGCCAATAAAATTGCCGTAATGTAATATCATTGAAGA CTAATGAATAAACAAAAACTTGCAATAACTAAAAAAAAAAAAAAAA Full BLAST >as:δ-hexatoxin-Hv1a_6 cDNA sequence (XenFW305) for δ-hexatoxin-Hv1a_6 from the Blue Mountains funnel-web spider Hadronyche versuta. TCTACCATAATGAAAATAACAGCAGCTTTGTACGTGCTCTTCTTTCTGACAATCGCTCTG GGCGACTTTACTGAAGGAAATGAAAATGACCTGGTGGAGAACCTACGTGCGGAACTTTCT GAGGCAGATATTCCACTATTGAAGAAACTGGAAGCAGCTGAAGATGTACTTTTGGAGAAA GATTTCTTGTCACATGCAGAGGAGGACAGAAGTGCACGTCCCAAGAGATGCGCTAAAAAA AGAAATTGGTGTGGTAAGACTGAAGACTGCTGCTGCCCGATGAAATGTGTATATGCCTGG TATAATGAGCAAGGTAGTTGCCAAAGTACTATTAGTGCGCTGTGGAAAAAGTGTTGATTC GCGAAAGCGAGAATTCAACGGCCAAATCTCTTGCTCCCTCGAGAACAAAAGATAAATCCG TATTAATTTTGAAATTCATGTTTAATCACTCAAATGCAACTGAAGTGAGAAATGTTATTT TAGTTGCTTGTGAACTCCTTCTTCGCCAATAAAATTGCCGTAATGTAATATCATTGAAGA CTAATGAATAAACAAAAACTTGCAATAACTAAAAAAAAAAAAAAAAA Full BLAST >as:δ-hexatoxin-Hv1a_7 cDNA sequence (XenFW306) for δ-hexatoxin-Hv1a_7 from the Blue Mountains funnel-web spider Hadronyche versuta. TCTACCATAATGAAAATACCAGCAGCTTTGTACGTGCTCTTCTTTCTGACAATCGCTCTG GGCGACTTTACTGAAGGAAATGAAAATGACCTGGTGGAGAACCTACGTGCGGAACTTTCT GAGGCAGATATTCCACTATTGAAGAAACTGGAAGCAGCTGAAGATGCACTTTTGGAGAAA GATTTCTTGTCACATGCAGAGGAGGACAGAAGTGCACGTCCCAAGAGATGCGCTAAAAAA AGAAATTGGTGTGGTAAGACTGAAGACTGCTGCTGCCCGATGAAATGTGTATATGCCTGG TATAATGAGCAAGGTAGTTGCCAAAGTACTATTAGTGCGCTGTGGAAAAAGTGTTGATTC GCGAAAGCGAGAATTCAACGGCCAAATCTCTTGCTCCCTCGAGAACAAAAGATAAATCCG TATTAATTTTGAAATTCATGTTTAATCACTCAAATGCAACTGAAGTGAGAAATGTTATTT TAGTTGCTTGTGAACTCCTTCTTCGCCAATAAAATTGCCGTAATGTAATATCATTGAAGA CTAATGAATAAACAAAAACTTGCAATAACTAAAAAAAAAAAAAAAAAAAAA Full BLAST >as:δ-hexatoxin-Hv1a_8 cDNA sequence (XenFW308) for δ-hexatoxin-Hv1a_8 from the Blue Mountains funnel-web spider Hadronyche versuta. TCTACCATAATGAAAATAACAGCAGCTTTGTACGTGCTCTTCTTTCTGACAATTGCTCTG GGCGACTTTACTGAAGGAAATGAAAATGACCTGGTGGAGAACCTACGTGCGGAACTTTCT GAGGCAGATATTCCACTATTGAAGAAACTGGAAGCAGCTGAAGATGCACTTTTGGAGAAA GATTTCTTGTCACATGCAGAGGAGGACAGAAGTGCACGTCCCAAGAGATGCGCTAAAAAA AGAAATTGGTGTGGTAAGACTGAAGACTGCTGCTGCCCGATGAAATGTGTATATGCCTGG TATAATGAGCAAGGTAGTTGCCAAAGTACTATTAGTGCGCTGTGGAAAAAGTGTTGATTC GCGCAAGCGAGAATTCAACGACCAAATCTCTTGCTCCCACGAGAACAAAAGATAAATCCG TATTAATTTTGAAATTCATGTTTAATTACTCAAATGCAACTGAAGTGAGAAATGTTATTT TAGTTGCTTGTGAACTCCTTCTTCGCCAATAAAATTGCCGTAATGTAATATCATTGAAGA CTAATGAATAAACAAAAACTTGCAATAACTAAAAAAAAAAAAAAAA Full BLAST >as:δ-hexatoxin-Hv1a_9 cDNA sequence (XenFW309) for δ-hexatoxin-Hv1a_9 from the Blue Mountains funnel-web spider Hadronyche versuta. TCTCCCATAATGAAAATAACAGCAGCTTTGTACGTGCTCTTCTTTCTGACAATCGCTCTG GGCGACTTTACTGAAGGAAATGAAAATGACCTGGTGGAGAACCTACGTGCGGAACTTTCT GAGGCAGATATTCCACTATTGAAGAAACTGGAAGCAGCTGAAGATGCACTTTTGGAGAAA GATTTCTTGTCACATGCAGAGGAGGACAGAAGTGCACGTCCCAAGAGATGCGCTAAAAAA AGAAATTGGTGTGGTAAGACTGAAGACTGCTGCTGCCCGATGAAATGTGTATATGCCTGG TATAATGAGCAAGGTAGTTGCCAAAGTACTATTAGTGCGCTGTGGAAAAAGTGTTGATTC GCGAAAGCGAGAATTCAACGGCCAAATCTCTTGCTCCCTCGAGAACAAAAGATAAATCCG TATTAATTTTGAAATTCATGTTTAATCACTCAAATGCAACTGAAGTGAGAAATGTTATTT TAGTTGCTTGTGAACTCCTTCTTCGCCAATAAAATTGCCGTAATGTAATATCATTGAAGA CTAATGAATAAACAAAAACTTGCAATAACTAAAAAAAAAAAAAAAAAAAAAAAAA Full BLAST >as:δ-hexatoxin-Hv1a_10 cDNA sequence (XenFW?) for δ-hexatoxin-Hv1a_10 from the Blue Mountains funnel-web spider Hadronyche versuta. TCTACCATAATGAAAATAACAGCAGCTTTGTACGTGCTCTTCTTTCTGACAATTGCTCTG GGCGACTTTACTGAAGGAAATGAAAATGACCTGGTGGAGAACCTACGTGCGGAACTTTCT GAGGCAGATATTCCACTATTGAAGAAACTGGAAGCAGCTGAAGATGCACTTTTGGAGAAA GATTTCTTGTCACATGCAGAGGAGGACAGAAGTGCACGTCCCAAGAGATGCGCTAAAAAA AGAAATTGGTGTGGTAAGACTGAAGACTGCTGCTGCCCGATGAAATGTGTATATGCCTGG TATAATGAGCAAGGTAGTTGCCAAAGTACTATTAGTGCGCTGTGGAAAAAGTGTTGATTC GCGCAAGCGAGAATTCAACGACCAAATCTCTTGCTCCCACGAGAACAAAAGATAAATCCG TATTAATTTTGAAATTCATGTTTAATTACTCAAATGCAACTGTAGTGAAAAATGTTATTT CAGTTGCTGGTGAACTCCTTCTTCGCCAATAAAATTGCTGTAATGTAATTTCGTTGAAGA CTAAGAATAAACAAAAACTTGCAATAACTAAAAAAAAAAAAAAAA Full BLAST >as:δ-hexatoxin-Hv1a_11 cDNA sequence (XenFW311) for δ-hexatoxin-Hv1a_11 from the Blue Mountains funnel-web spider Hadronyche versuta. TCTACCATAATGAAAATACCAGCAGCTTTGTACGTGCTATTCTTTCTGACAATTGCTCTG GGCGACTTTACTGAAGGAAATGAAAATGACCTGGTGGAGAACCTACGTGCGGAACTTTCT GAGGCAGATATTCCACTATTGAAGAAACTGGAAGCAGCTGAAGATGCACTTTTGGAGAAA GATTTCTTGTCACATGCAGAGGAGGACAGAAGTGCACGTCCCAAGAGATGCGCTAAAAAA AGAAATTGGTGTGGTAAGACTGAAGACTGCTGCTGCCCGATGAAATGTGTATATGCCTGG TATAATGAGCAAGGTAGTTGCCAAAGTACTATTAGTGCGCTGTGGAAAAAGTGTTGATTC GCGCAAGCGAGAATTCAACGACCAAATCTCTTGCTCCCACGAGAACAAAAGATAAATCCG TATTAATTTTGAAATTCATGTTTAATTACTCAAATGCAACTGTAGTGAAAAATGTTATTT CAGTTGCTGGTGAACTCCTTCTTCGCCAATAAAATTGCTGTAATGTAATTTCGTTGAAGA CTAATGAATAAACAAAAACTTGCAATAACTAAAAAAAAAAAAAAAAA Full BLAST >as:δ-hexatoxin-Hv1a_12 cDNA sequence (XenFW312) for δ-hexatoxin-Hv1a_12 from the Blue Mountains funnel-web spider Hadronyche versuta TCTACCATAATGAAAATACCAGCAGCTTTGTACGTGCTATTCTTTCTGACAATTGCTCTG GGCGACTTTACTGAAGGAAATGAAAATGACCTGGTGGAGAACCTACGTGCGGAACTTTCT GAGGCAGATATTCCACTATTGAAGAAACTGGAAGCAGCTGAAGATGCACTTTTGGAGAAA GATTTCTTGTCACATGCAGAGGAGGACAGAAGTGCACGTCCCAAGAGATGCGCTAAAAAA AGAAATTGGTGTGGTAAGACTGAAGACTGCTGCTGCCCGATGAAATGTGTATATGCCTGG TATAATGAGCAAGGTAGTTGCCAAAGTACTATTAGTGCGCTGTGGAAAAAGTGTTGATTC GCGCAAGCGAGAATTCAACGACCAAATCTCTTGCTCCCACGAGAACAAAAGATAAATCCG TATTAATTTTGAAATTCATGTTTAATTACTCAAATGCAACTGTAGTGAAAAATGTTATTT CAGTTGCTGGTGAACTCCTTCTTCGCCAATAAAATTGCTGTAATGTAATTTCGTTGAAGA CTAATGAATAAACAAAAACTTGCAATAACTAAAAAAAAAAAAAAAAA Full BLAST >as:δ-hexatoxin-Hv1a_13 cDNA sequence (XenFW313) for δ-hexatoxin-Hv1a_13 from the Blue Mountains funnel-web spider Hadronyche versuta GTCTACCTAATGAAAATAACAGCAGCTTTGTACGTGCTCTTCTTTCTGACAATCGCTCTG GGCGACTTTACTGAAGGAAATGAAAATGACCTGGTGGAG---------AACCTACGTGCG GAACTTTCTGAGGCAGATATTCCACTATTGAAGAAACTGGAAGCAGCTGAAGATGCACTT TTGGAGAAAGATTTCTTGTCACATGCAGAGGAGGACAGAAGTGCACGTCCCAAGAGATGC GCTAAAAAAAGAAATTGGTGTGGTAAGACTGAAGACTGCTGCTGCCCGATGAAATGTGTA TATGCCTGGTATAATGAGCAAGGTAGTTGCCAAAGTACTATTAGTGCGCTGTGGAAAAAG TGTTGATTCGCGAAAGCGAGAATTCAACGGCCAAATCTCTTGCTCCCTCGAGAACAAAAG ATAAATCCGTATTAATTTTGAAATTCATGTTTAATCACTCAAATGCAACTGAAGTGAGAA ATGTTATTTTAGTTGCTTGTGAACTCCTTCTTCGCCAATAAAATTGCCGTAATGTAATAT CATTGAAGACTAATGAATAAACAAAAACTTGCAATAACTAAAAAAAAAAAAAAAAAAA Full BLAST >as:δ-hexatoxin-Hv1a_14 cDNA sequence (XenFW303) for δ-hexatoxin-Hv1a_14 from the Blue Mountains funnel-web spider Hadronyche versuta. ATGAAAATACCAGCAGCTTTGTACGTGCTCTTCTTTCTGACAATCGCTCTGGGCGACTTT ACTGAAGGAAATGAAAATGACCTGGTGGAGAACCTACGTGCGGAACTTTCTGAGGCAGAT ATTCCACTATTGAAGAAACTGGAAGCAGCTGAAGATGCACTTTTGGAAAACGATTTCCTG CCACATGCAGAGGAGGACAGAAGTGCACGTCCCAAGAGATGCGCTAAAAAAAGAAATTGG TGTGGTAAGACTGAAGACTGCTGCTGCCCGATGAAATGTGTATATGCCTAGTATAATGAG CAAGGTAGTTGCCAAAGTACTATTAGTGCGCTGTGGAAAAAGTGTTGA Full BLAST Toxin Synonyms Synonym Type δ-hexatoxin-Hv1a Recommended full name δ-HXTX-Hv1a Recommended abbreviation δ-atracotoxin-Hv1a Synonym Versutoxin Synonym δ-ACTX-Hv1a Synonym (abbreviation) VTX Synonym (abbreviation) Toxin Structure Please click a structure to view:
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