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| Toxin Name |
U1-aranetoxin-Av1a |
| Source Species |
Araneus ventricosus (Orbweaver spider) |
| Toxin Group |
Aranetoxin |
| Description |
Insecticidal toxin from the spider Araneus ventricosus. Contains a BPTI/Kunitz inhibitor domain. |
| Discovered |
2002 |
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| This toxin last updated on Jan 29, 2009 |
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| Current Taxonomy |
Historic Taxonomy |
| Kingdom |
Animalia |
| Phylum |
Arthropoda |
| Class |
Arachnida |
| Order |
Araneae |
| Infra-order |
Araneomorphae |
| Family |
Araneidae |
| Genus |
Araneus |
| Species |
ventricosus |
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| Aranea pia |
| Aranea piata |
| Araneus ventricosa |
| Araneus ventricosus |
| Cathaistela ventricosa |
| Epeira senta |
| Epeira ventricosa |
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| Molecular Target |
ED50 |
IC50 |
Kd |
Pharmacophore |
Comment |
| Serine protease inhibitor |
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| Original Deposition References |
Jung E.H., Lee K.S., Han J.H., Je Y.H., Chang J.H., Roh J.Y., Sohn H.D., Jin B.R.
Int. J. Ind. Entomol. 4:43-49(2002).
Molecular cloning of two cDNAs encoding an insecticidal toxin from the spider, Araneus ventricosus, and construction of a recombinant baculovirus expressing a spider toxin.
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| Peptide Sequences |
>as:U1-aranetoxin-Av1a|sp:Q8T3S7 Insecticidal toxin U1-aranetoxin-Av1a from the spider Araneus ventricosus
MPFHYFPKLNPITWIPGWIPGLGKDRCLLPKVTGPCKASLTRYYYDKDTKACVEFIYGGC
RGNRNNFKRKDECEKACTDH |
Full BLAST |
BLAST mature toxin only
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| mRNA Sequences |
>as:U1-aranetoxin-Av1a|gb:AY091482 cDNA sequence encoding toxin U1-aranetoxin-Av1a from the spider Araneus ventricosus
ATGCCTTTCCACTACTTTCCCAAACTGAATCCTATAACCTGGATCCCTGGATGGATTCCT
GGTTTGGGTAAAGATAGATGCCTTCTTCCGAAGGTAACAGGACCTTGCAAAGCTAGTCTG
ACCCGTTACTATTATGACAAGGACACCAAAGCATGCGTGGAATTCATCTACGGTGGCTGC
AGAGGAAACAGGAACAATTTCAAACGGAAAGATGAGTGCGAAAAAGCCTGCACGGATCAC
TAA |
Full BLAST
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| Synonym |
Type |
| U1-aranetoxin-Av1a |
Recommended full name |
| U1-AATX-Av1a |
Recommended abbreviation |
| Toxin 1 |
Synonym |
| AvTox1 |
Synonym (abbreviation) |
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