Toxin Name U2-agatoxin-Aop1a
Source Species Allagelena  opulenta
Toxin Group Agatoxin
Description Insecticidal toxin causing rapid but reversible paralysis in crickets. No activity shown in mammals. Suppresses the excitatory post-synaptic potentials evoked in lobster neuromuscular synaptic preparations, possibly by blocking the presynaptic calcium channel. Does not bind to mammalian voltage-gated calcium channel subtypes Cav2.1, Cav2.2 or Cav2.3. The toxin sequence is identical to the insecticidal U2-agatoxin-Ao1a from the venom of the related species Agelena orientalis
Discovered 1990
no image
This toxin last updated on Aug 20, 2010

Biological Activity
Literature References
Protein Information
Toxin Synonyms
Toxin Structure